Availability: In StockBiological Description:Bisoprolol is a selective type β1 adrenergic receptor blocker.Target: Adrenergic ReceptorApproved: July 31, 1992Bisoprolol, on beta 1-adrenoceptor peptide induced autoimmune myocardial damage. In the animal model of autoimmune cardiomyopathy induced by active immunization of rabbits with beta 1-adrenoceptor peptide, bisoprolol was given at a dose of 3 mg/day throughout the study period. Our results showed high titer of anti-beta 1-adrenoceptor antibody in the immunized group throughout the study but not in the group receiving only bisoprolol [1]. Bisoprolol administration resulted in a significant reduction in HR reaching 60.3 +/- 1.4 bpm at VT of 500 mL (compared to 70.5 +/- 1.8 bpm with placebo, P < 0.001).="" changes="" in="" hp="" were="" also="" significant="" with="" an="" increase="" in="" hp="" reaching="" 1004.5="" +/-="" 22.2="" msec="" at="" this="" controlled="" vt="" (compared="" to="" 860.3="" +/-="" 21.5="" msec="" with="" placebo,="" p="">< 0.001)="">Toxicity: Oral, mouse: LD50 = 100 mg/kg; Skin, rabbit: LD50 = 200 mg/kg; Skin, rat: LD50 = 500 mg/kg. Symptoms of overdo...Purity: >98%Molecular formula: C₄₀H₆₆N₂O₁₂Molecular Weight: 766.96Storage Instructions: Two years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSOReferences: for more information, please visit images/AffixScientific/

Affix Scientific国烟草货号： 1185887-21-1生物学描述：AB-FUBINACA是一种基于吲唑的合成大麻素（CB），其对中央CB1受体的亲和力（Ki = 0.9 nM）比JWH 018高10倍。AB-FUBINACA最初是由辉瑞公司（Pfizer，Inc.）合成的。一种有效的CB1受体调节剂，可用于潜在的治疗用途，但最近在非法草药产品中与AB-PINACA一起被发现。1,2AB-CHMINACA与AB-FUBINACA在结构上相关，但环己基取代了4-氟苯基。该化合物的生理和毒理特性尚未确定。该产品用于研究和法医应用。纯度： ≥98％分子式： C 2 0 H 2 8 N 4O 2分子量： 129.15贮存说明： -20°C粉末，2周DMSO中4°C，6个月-DMSO中80°C，2年