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当前位置: 首页 > 产品中心 > Biochemical_standard > 西药/(+)-酮康唑/5g/142128-59-4
商品详细西药/(+)-酮康唑/5g/142128-59-4
西药/(+)-酮康唑/5g/142128-59-4
西药/(+)-酮康唑/5g/142128-59-4
商品编号: 142128-59-4
品牌: affixscientific
市场价: ¥10816.00
美元价: 5408.00
产地: 美国(厂家直采)
公司:
产品分类: 生化标准品
公司分类: Biochemical_standard
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
Availability: In Stock
Cat No.: 142128-59-4
Biological Description:(+)-Ketoconazole is an imidazole anti-fungal agent, a CYP3A4 inhibitor.Target: CYP3A4 (+)-Ketoconazole, an imidazole anti-fungal agent, has often produced features of androgen deficiency including decreased libido, gynecomastia, impotence, oligospermia, and decreased testosterone levels, in men being treated for chronic mycotic infections [1]. (+)-Ketoconazole also is a cytochrome P450 inhibitor [2].(+)-Ketoconazole (KTZ), on the antischistosomal potential of these quinolines against Schistosoma mansoni infection by evaluating parasitological, histopathological, and biochemical parameters. Mice were classified into 7 groups: uninfected untreated (I), infected untreated (II), infected treated orally with PZQ (1,000 mg/kg) (III), QN (400 mg/kg) (IV), KTZ (10 mg/kg)+QN as group IV (V), HF (400 mg/kg) (VI), and KTZ (as group V)+HF (as group VI) (VII). KTZ plus QN or HF produced more inhibition (P<0.05) in="" hepatic="" cyp450="" (85.7%="" and="" 83.8%)="" and="" cyt="" b5="" (75.5%="" and="" 73.5%)="" activities,="" respectively,="" than="" in="">Purity: >98%Molecular formula: C26H28Cl2N4O4Molecular Weight: 531.43Storage Instructions: Two years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSOReferences: for more information, please visit images/AffixScientific/
品牌介绍
Affix Scientific国烟草货号: 1185887-21-1生物学描述:AB-FUBINACA是一种基于吲唑的合成大麻素(CB),其对中央CB1受体的亲和力(Ki = 0.9 nM)比JWH 018高10倍。AB-FUBINACA最初是由辉瑞公司(Pfizer,Inc.)合成的。一种有效的CB1受体调节剂,可用于潜在的治疗用途,但最近在非法草药产品中与AB-PINACA一起被发现。1,2AB-CHMINACA与AB-FUBINACA在结构上相关,但环己基取代了4-氟苯基。该化合物的生理和毒理特性尚未确定。该产品用于研究和法医应用。纯度: ≥98%分子式: C 2 0 H 2 8 N 4O 2分子量: 129.15贮存说明: -20°C粉末,2周DMSO中4°C,6个月-DMSO中80°C,2年